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TB-500 5 mg vial — Research Use Only

Cap colour may vary by batch.

For research use only

TB-500

Synthetic fragment of Thymosin β4 — in vitro study tool for cell migration and angiogenesis.

DosagePurity ≥ 99.0% (HPLC)
€64.00per 5 mg vial

i.e. €12.80 per mg

QuantityHalloween 2 + 1

3 vials: the cheapest item is free at checkout. Estimate for this product alone; the discount is applied at payment, across your whole cart.

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Shipped within 24 business hours from France, in neutral packaging.

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Janoshik certificateAnalysis no. 89630, purity 99.188% (10.88 mg)Commissioned by: third-party reportVerify
A question about this product?

Research Use Only — Laboratory use exclusively. Not intended for veterinary, diagnostic or therapeutic use. No indication for in vivo use. To be handled exclusively by qualified personnel.

Literature

What the literature describes

TB-500 reproduces the active sequence of Thymosin β4 (Tβ4), an endogenous peptide involved in regulating the actin cytoskeleton. Studies (PMID 14500546, PMID 11311852) describe sequestration of G-actin, modulating F-actin polymerization and promoting cell migration (keratinocytes, endothelial cells, stem cells). At the angiogenic level, TB-500 stimulates capillary tube formation by HUVECs and activates the PINCH-ILK-α-parvin pathway. Preclinical models also describe modulation of pro-inflammatory cytokines. No direct hormonal effect has been reported. These data come from the scientific literature and are provided strictly for informational purposes in a research context. This product is not intended for veterinary, diagnostic or therapeutic use and is not recommended for any use outside a scientific, professional and research setting. [1][2]

Research background
Synthetic peptide corresponding to an active fragment of Thymosin β4, used for the in vitro study of G-actin sequestration.
Reconstitution (lab)
Sterile bacteriostatic water. Dilution calculator

Chemical identity

What the vial contains

Reference data for the compound. Measured values appear on the Janoshik certificate, when published.

Research name
TB-500
CAS No.
77591-33-4
Molecular formula
C212H350N56O78S
Molecular weight
4963.4 g/mol
Specified purity
≥ 99.0% (HPLC)
Vial content
5 mg
Storage
Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
Database
PubChem

Independent analysis

Certificate for 5 mg

Report from Janoshik Analytical, an independent laboratory, for this exact dosage. The data below are taken from the report.

Janoshik certificate for this dosageCommissioned by: third-party report
Purity
99.188% (10.88 mg)
Janoshik task
#89630
Tested
21/11/2025

Questions

Frequently asked questions

What does a vial of TB-500 contain?

Each vial contains lyophilised TB-500, available in 5 mg. Purity ≥ 99.0% (HPLC), tested by an independent laboratory.

How can I check the purity of TB-500?

The Janoshik Analytical (independent laboratory) certificates we hold are shown on this page for the matching dosage and can be verified directly on the laboratory's website. For a dosage without a published certificate, testing is in progress or available on request.

How should TB-500 be stored?

Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).

How is TB-500 reconstituted in the laboratory?

Sterile bacteriostatic water. The site's dilution calculator helps prepare the desired concentration.

Is TB-500 intended for human use?

No. TB-500 is a research reagent (RUO) intended exclusively for in vitro laboratory research. It is not intended for human or veterinary use, nor for diagnosing, preventing or treating any disease.

References

Cited sources

  1. [1]PubMedPMID 10469335PubMed · 10469335View on PubMed
  2. [2]PubMedPMID 17600280PubMed · 17600280View on PubMed

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