Practice· 7 min
Good Practice for Reconstituting a Lyophilized Peptide in the Laboratory
Solvent choice, sterile consumables, wall-flow technique, gentle homogenization: how a clean reconstitution actually runs.
Read the article →Laboratory journal
The Peptinium Notebook
Analytical methodology, scientific history and how to read a certificate of analysis. Filter by category to jump straight to your topic.
— Featured
— Safety & RUO
Safety & RUO· 6 min
Lyophilized or Reconstituted: Storage Rules in the Laboratory
Temperatures, reference durations, light exposure, freeze/thaw cycles: the storage framework applying to peptide reagents in a laboratory setting.
Read the article →Safety & RUO· 7 min
"Research Use Only": What the Label Actually Means
Where the RUO label comes from, what it allows, what it excludes, and the practical obligations it implies for a purchasing laboratory.
Read the article →Safety & RUO· 7 min
Traceability and Third-Party Quality Control: Assessing a Peptide Reagent Supplier
Lot traceability chain, independence of the analytical laboratory, documentary consistency: the objective criteria for judging a supplier.
Read the article →Safety & RUO· 7 min
The Legal Framework for Research Peptides in France: What the 2026 Regulations Say
RUO, marketing authorization, unlicensed practice of pharmacy: what the French regulatory framework actually says about research peptides, and where RT-3 stands.
Read the article →— Science
Science· 6 min
GHK-Cu: what the literature documents about the copper-tripeptide of tissue regeneration
An endogenous copper-peptide complex capable of modulating the expression of several thousand genes in vitro: an overview of the literature devoted to GHK-Cu.
Read the article →Science· 6 min
CJC-1295 and Ipamorelin: the GHRH / GHS-R1a synergy in the literature on the somatotropic axis
A GHRH analog paired with a selective GH secretagogue: what the pharmacological literature documents on this widely studied combination in research.
Read the article →Science· 6 min
Semax: a review of the research literature on this ACTH-derived neurotrophic peptide
A heptapeptide devoid of corticotropic activity, studied for its influence on BDNF and NGF: an overview of the research literature on Semax.
Read the article →Science· 7 min
Melanotan I and II: what the literature says about these α-MSH analogs
MC1R selectivity versus non-selective MC1R/MC3R/MC4R activation: an editorial comparison of two analogs of the melanotropic hormone studied in research.
Read the article →Science· 7 min
Glutathione: what the literature documents about this reference antioxidant tripeptide
Major intracellular redox buffer, enzymatic cofactor, oxidative stress marker: glutathione is one of the most studied tripeptides in cell biology.
Read the article →Science· 7 min
KLOW: the scientific rationale behind this four-peptide repair blend
GHK-Cu, BPC-157, TB-500 and KPV combined in a single protocol: why the literature studies these four mechanisms as complementary rather than redundant.
Read the article →Science· 7 min
Cagrilintide: what the literature says about this long-acting amylin analog
An acylated, stabilized analog of human amylin, cagrilintide is studied for its non-selective activation of AMY receptors and its half-life compatible with weekly protocols.
Read the article →Science· 6 min
KissPeptin-10: the reproductive axis switch studied via the GPR54 receptor
An active fragment of the KISS1 protein, this decapeptide is described in the literature as the upstream trigger of pulsatile GnRH secretion.
Read the article →Science· 7 min
RT-3: a synthesis of the research literature on the triple GLP-1/GIP/glucagon agonist
A triple GLP-1/GIP/glucagon agonist still in phase 3 clinical trials: editorial synthesis of what the published pharmacological literature documents on RT-3.
Read the article →Science· 7 min
BPC-157 and TB-500: what preclinical research literature says about tissue repair
Angiogenesis, cell migration, rodent models: what the published preclinical literature documents on BPC-157 and TB-500 — two peptides frequently studied together.
Read the article →Science· 6 min
AHK-Cu: what the literature documents about this second copper tripeptide
Less well known than its cousin GHK-Cu, AHK-Cu is studied for its action on the hair follicle and the extracellular matrix: an overview of the research literature.
Read the article →Science· 6 min
Tesamorelin: the clinical literature on this stabilized GHRH analog
Protected against DPP-IV degradation, this GHRH analog has been the subject of published clinical trials on visceral adipose tissue: a review of the literature.
Read the article →Science· 7 min
NAD+: what the literature documents about this central cofactor of cellular metabolism
An obligatory substrate for sirtuins and PARPs, NAD+ declines with age: a review of the research literature on this central coenzyme of energy metabolism.
Read the article →Science· 6 min
PT-141 (Bremelanotide): a melanocortin analog refined for MC4R/MC3R selectivity
Derived from Melanotan II but designed to reduce the pigmentary effect, PT-141 illustrates the logic of receptor selectivity in melanocortin pharmacology.
Read the article →Science· 6 min
Oxytocin: what the literature says about the OXTR receptor and its peripheral effects
Beyond its role in social behavior, oxytocin also acts on the uterus, mammary glands, and bone metabolism: an overview of the research literature.
Read the article →Science· 6 min
Selank: the Russian literature on this stabilized tuftsin analog
With no direct affinity for the GABA-A receptor but capable of potentiating GABAergic transmission: what the literature documents about Selank.
Read the article →Science· 6 min
DSIP: the literature on this nonapeptide associated with delta sleep
Originally isolated from the blood of rabbits in deep sleep, DSIP is studied for its influence on delta waves, the stress axis, and oxidative stress.
Read the article →Science· 6 min
Epithalon: what the literature documents about this tetrapeptide and telomerase
Inspired by a pineal extract, this four-amino-acid tetrapeptide is studied for its influence on telomerase expression and cellular senescence.
Read the article →Science· 6 min
KPV: the smallest active fragment of α-MSH studied for the NF-κB pathway
Three amino acids, no melanocortin affinity, but a reported action on the inflammatory NF-κB pathway: what the literature documents about KPV.
Read the article →Science· 7 min
Research Peptides: History, Science, and Their Current Place in the Literature
From Emil Fischer's early work to Merrifield's solid-phase synthesis: a scientific overview of peptides used in basic research.
Read the article →Science· 7 min
MOTS-c: the peptide encoded by mitochondrial DNA studied for the AMPK pathway
Encoded not by the nucleus but by mitochondrial DNA itself, MOTS-c illustrates a recent discovery in metabolic biology: the mitochondrion as a source of signaling peptides.
Read the article →Science· 6 min
SNAP-8: a mimetic octapeptide studied for its competition with the SNARE complex
By mimicking a fragment of the SNAP-25 protein, this synthetic peptide is studied for its interference with calcium-dependent neuronal exocytosis.
Read the article →— Practice
Practice· 6 min
Laboratory Syringes and Needles: Understanding Formats and Choosing Well
Volume, graduation, gauge, length, luer fitting vs. fixed needle: how consumable format conditions the precision of a withdrawal.
Read the article →Practice· 6 min
Organizing a Peptide Reagent Inventory: Lots, Labeling, and Rotation
Lot log, labeling convention, FEFO rotation, storage zones, and temperature monitoring: how to structure a usable inventory.
Read the article →Practice· 5 min
Receipt Checklist for a Research Reagent Order
Package inspection, vial and lot verification, matching against CoAs, immediate storage: the ten-point procedure.
Read the article →Practice· 6 min
Stability and Cold Chain: The Science of Peptide Preservation
Why a lyophilized peptide remains stable for months while a solution degrades within weeks. A physicochemical look at preservation.
Read the article →— Methodology
Methodology· 6 min
Reconstituting lyophilized peptides: dilution calculation methodology
Concentration, solvent volume, graduated syringe units: the methodology behind the dilution calculation for reconstituting a lyophilized peptide, without dosage recommendations.
Read the article →Methodology· 6 min
NA Selank Amidate: a stabilized form of Selank studied for its enzymatic resistance
N-terminal acetylation and C-terminal amidation: two classic chemical modifications applied to Selank to extend its half-life in in vitro protocols.
Read the article →Methodology· 8 min
HPLC Purity ≥ 99%: How to Interpret a Certificate of Analysis
Chromatography, mass spectrometry, lot-by-lot traceability: what a Janoshik CoA actually demonstrates and why it matters.
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