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SNAP-8 10 mg vial — Research Use Only

Cap colour may vary by batch.

For research use only

SNAP-8

Octapeptide mimetic of the N-terminal domain of SNAP-25 — in vitro study tool for the SNARE complex.

DosagePurity ≥ 99.0% (HPLC)
€59.00per 10 mg vial

i.e. €5.90 per mg

QuantityHalloween 2 + 1

3 vials: the cheapest item is free at checkout. Estimate for this product alone; the discount is applied at payment, across your whole cart.

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A question about this product?

Research Use Only — Laboratory use exclusively. Not intended for veterinary, diagnostic or therapeutic use. No indication for in vivo use. To be handled exclusively by qualified personnel.

Literature

What the literature describes

SNAP-8 is an octapeptide mimetic of the N-terminal domain of the SNAP-25 protein, an essential component of the SNARE complex that regulates the fusion of synaptic vesicles with the presynaptic membrane. The mechanism put forward for this mimetic is partial competition with endogenous SNAP-25, which would reduce SNARE complex formation and attenuate calcium-dependent neurotransmitter release; published work addresses fragments of SNAP-25 itself (PMID 10882724, 26098518), while the literature specific to SNAP-8 remains very limited. At the skin level, preclinical models report a transient reduction in facial muscle contractions (local myorelaxant effect) without systemic diffusion. No hormonal effect has been documented. These data come from the scientific literature and are provided strictly for informational purposes in a research context. This product is not intended for veterinary, diagnostic or therapeutic use and is not recommended for any use outside a scientific, professional and research setting. [1][2]

Research background
Synthetic peptide used as an in vitro research tool for modulating neuronal exocytosis and the SNARE complex.
Reconstitution (lab)
Sterile bacteriostatic water. Dilution calculator

Chemical identity

What the vial contains

Reference data for the compound. Measured values appear on the Janoshik certificate, when published.

Research name
SNAP-8
CAS No.
868844-74-0
Molecular formula
C40H67N11O13
Molecular weight
910.03 g/mol
Specified purity
≥ 99.0% (HPLC)
Vial content
10 mg
Storage
Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
Database
PubChem

Independent analysis

Certificate for 10 mg

No Janoshik certificate has been published for 10 mg yet. We never show another dosage's report in its place.

No certificate published for this dosage

Questions

Frequently asked questions

What does a vial of SNAP-8 contain?

Each vial contains lyophilised SNAP-8, available in 10 mg. Purity ≥ 99.0% (HPLC), tested by an independent laboratory.

How should SNAP-8 be stored?

Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).

How is SNAP-8 reconstituted in the laboratory?

Sterile bacteriostatic water. The site's dilution calculator helps prepare the desired concentration.

Is SNAP-8 intended for human use?

No. SNAP-8 is a research reagent (RUO) intended exclusively for in vitro laboratory research. It is not intended for human or veterinary use, nor for diagnosing, preventing or treating any disease.

References

Cited sources

  1. [1]PubMedPMID 10882724PubMed · 10882724View on PubMed
  2. [2]PubMedPMID 26098518PubMed · 26098518View on PubMed

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