

Cap colour may vary by batch.
For research use only
Semax
Synthetic heptapeptide derived from ACTH(4-10) — in vitro research tool for neurotrophic pathways.
i.e. €7.40 per mg
3 vials: the cheapest item is free at checkout. Estimate for this product alone; the discount is applied at payment, across your whole cart.
In stock
Shipped within 24 business hours from France, in neutral packaging.
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Buy 3 items and the cheapest one is free: peptides, packs, pens or accessories, everything counts, and each unit counts as one item. 6 items = 2 free, 9 = 3 free (3 maximum per order). Offer not combinable with promo codes, applied automatically at checkout. Until 31 October inclusive.
Research Use Only — Laboratory use exclusively. Not intended for veterinary, diagnostic or therapeutic use. No indication for in vivo use. To be handled exclusively by qualified personnel.
Literature
What the literature describes
Semax is a heptapeptide derived from the ACTH(4-10) fragment with no corticotropic activity. Studies (PMID 16996037, 16635254) demonstrated a rapid increase in the expression of BDNF (Brain-Derived Neurotrophic Factor) and NGF (Nerve Growth Factor) in the hippocampus and frontal cortex of murine models, as well as modulation of TrkA/TrkB receptors. At the hormonal level, unlike ACTH(1-24) fragments, Semax does not stimulate the HPA axis and does not elevate cortisol. The studies describe modulation of the dopaminergic, serotonergic, and cholinergic systems, an increase in endogenous enkephalin, and a reduction in neuronal oxidative stress. Functionally, the studies observe improved memory and attention performance in models of cerebral ischemia and stroke, as well as a neuroprotective effect via inhibition of BAX-mediated neuronal apoptosis. These data come from the scientific literature and are provided strictly for informational purposes in a research context. This product is not intended for veterinary, diagnostic or therapeutic use and is not recommended for any use outside a scientific, professional and research setting. [1][2][3]
- Research background
- Nootropic peptide studied in vitro for its effect on BDNF and NGF expression in neuronal models.
- Reconstitution (lab)
- Sterile bacteriostatic water. Dilution calculator
Chemical identity
What the vial contains
Reference data for the compound. Measured values appear on the Janoshik certificate, when published.
- Research name
- Semax
- CAS No.
- 80714-61-0
- Molecular formula
- C37H51N9O10S
- Molecular weight
- 813.92 g/mol
- Specified purity
- ≥ 99.0% (HPLC)
- Vial content
- 10 mg
- Storage
- Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
- Database
- PubChem
Independent analysis
Certificate for 10 mg
Report from Janoshik Analytical, an independent laboratory, for this exact dosage. The data below are taken from the report.
- Purity
- 99.500% (10.58 mg)
- Janoshik task
- #151275
- Tested
- 22/04/2026
Questions
Frequently asked questions
What does a vial of Semax contain?
Each vial contains lyophilised Semax, available in 10 mg. Purity ≥ 99.0% (HPLC), tested by an independent laboratory.
How can I check the purity of Semax?
The Janoshik Analytical (independent laboratory) certificates we hold are shown on this page for the matching dosage and can be verified directly on the laboratory's website. For a dosage without a published certificate, testing is in progress or available on request.
How should Semax be stored?
Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
How is Semax reconstituted in the laboratory?
Sterile bacteriostatic water. The site's dilution calculator helps prepare the desired concentration.
Is Semax intended for human use?
No. Semax is a research reagent (RUO) intended exclusively for in vitro laboratory research. It is not intended for human or veterinary use, nor for diagnosing, preventing or treating any disease.
References
Cited sources
- [1]PubMedPMID 29798983PubMed · 29798983View on PubMed
- [2]PMCPMC11498467PMC · PMC11498467View on PMC
- [3]PMCPMC8855339PMC · PMC8855339View on PMC
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