NA Selank Amidate

N-acetylated amidated form of Selank — in vitro research reagent for the study of peptide stability and neurotrophic pathways.

DosagePurity ≥ 99.0% (HPLC)

€139.00per 30 mg vial

i.e. €4.63 per mg

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Research Use Only — Laboratory use exclusively. Not intended for veterinary, diagnostic or therapeutic use. No indication for in vivo use. To be handled exclusively by qualified personnel.

Literature

What the literature describes

NA Selank Amidate is a structural modification of Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) featuring an N-terminal acetyl group and C-terminal amidation. These two modifications increase peptide resistance to aminopeptidases and carboxypeptidases, extending the in vitro half-life relative to the native form. Studies on Selank (PMID 31625062, PMC5322660) show modulation of hippocampal BDNF and NGF expression, potentiation of GABAergic transmission without direct binding to the GABA-A receptor, and reduced cortisol under acute stress conditions. The N-acetyl-amidated form is studied as a more stable analog for in vitro protocols of neuroprotection, synaptic plasticity, and cytokine modulation (IL-6, IFN-α). Behaviorally, the literature reports anxiolytic effects without sedation, improved memory and attention, and mild immunomodulation. These data come from the scientific literature and are provided strictly for informational purposes in a research context. This product is not intended for veterinary, diagnostic or therapeutic use and is not recommended for any use outside a scientific, professional and research setting. [1][2][3]

Research background: Synthetic peptide derived from Selank by N-terminal acetylation and C-terminal amidation, used as an experimental tool to compare metabolic stability, bioavailability, and modulation of BDNF expression in neuronal models.
Reconstitution (lab): Reconstitute with sterile bacteriostatic water. Clear, colorless solution. Dilution calculator

Chemical identity

What the vial contains

Reference data for the compound. Measured values appear on the Janoshik certificate, when published.

Research name: NA Selank Amidate
CAS No.: 129954-34-3 (dérivé N-acétyl-amidé)
Molecular formula: C35H59N12O9
Molecular weight: 779.92 g/mol
Specified purity: ≥ 99.0% (HPLC)
Vial content: 30 mg
Storage: Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).

Independent analysis

Certificate for 30 mg

No Janoshik certificate has been published for 30 mg yet. We never show another dosage's report in its place.

No certificate published for this dosage

All published certificates

Questions

Frequently asked questions

What does a vial of NA Selank Amidate contain?

Each vial contains lyophilised NA Selank Amidate, available in 30 mg. Purity ≥ 99.0% (HPLC), tested by an independent laboratory.

How should NA Selank Amidate be stored?

Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).

How is NA Selank Amidate reconstituted in the laboratory?

Reconstitute with sterile bacteriostatic water. Clear, colorless solution. The site's dilution calculator helps prepare the desired concentration.

Is NA Selank Amidate intended for human use?

No. NA Selank Amidate is a research reagent (RUO) intended exclusively for in vitro laboratory research. It is not intended for human or veterinary use, nor for diagnosing, preventing or treating any disease.

References