NAD+

Nicotinamide Adenine Dinucleotide — reference cofactor for in vitro study of cellular energy metabolism.

DosagePurity ≥ 99.0% (HPLC)

€109.00per 1000 mg vial

i.e. €0.11 per mg

QuantityHalloween 2 + 1

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Janoshik certificateAnalysis no. 75743, purity Quantification 973.33 / 992.04 mgCommissioned by: third-party reportView report

A question about this product?

Research Use Only — Laboratory use exclusively. Not intended for veterinary, diagnostic or therapeutic use. No indication for in vivo use. To be handled exclusively by qualified personnel.

Literature

What the literature describes

NAD+ (Nicotinamide Adenine Dinucleotide) is an essential cofactor for cellular oxidation-reduction reactions and the obligatory substrate of sirtuins (SIRT1-7), PARPs (Poly-ADP-ribose polymerases), and CD38. Studies (PMC10692436, PMC9512238, PMID 37971292) describe a progressive decline in intracellular NAD+ levels with age, correlated with a decline in mitochondrial function and DNA repair. Elevating NAD+ levels in vitro restores SIRT3 activity (deacetylation of mitochondrial proteins), improves fatty acid β-oxidation, and stimulates mitochondrial biogenesis via the PGC-1α pathway. At the hormonal level, the studies describe improved insulin sensitivity and modulation of tryptophan metabolism via the kynurenine pathway. Observed effects include reduced markers of cellular senescence (p16, p21) and increased autophagy. These data come from the scientific literature and are provided strictly for informational purposes in a research context. This product is not intended for veterinary, diagnostic or therapeutic use and is not recommended for any use outside a scientific, professional and research setting. [1][2][3]

Research background: Central redox coenzyme used as an in vitro research tool for the study of sirtuins and mitochondrial metabolism.
Reconstitution (lab): Sterile bacteriostatic water. Dilution calculator

Chemical identity

What the vial contains

Reference data for the compound. Measured values appear on the Janoshik certificate, when published.

Research name: NAD+
CAS No.: 53-84-9
Molecular formula: C21H27N7O14P2
Molecular weight: 663.43 g/mol
Specified purity: ≥ 99.0% (HPLC)
Vial content: 1000 mg
Storage: Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
Database: PubChem

Independent analysis

Certificate for 1000 mg

Report from Janoshik Analytical, an independent laboratory, for this exact dosage. The data below are taken from the report.

Janoshik certificate for this dosageCommissioned by: third-party report

Purity: Quantification 973.33 / 992.04 mg
Janoshik task: #75743
Tested: 20/08/2025

View the report All published certificates

Questions

Frequently asked questions

What does a vial of NAD+ contain?

Each vial contains lyophilised NAD+, available in 1000 mg. Purity ≥ 99.0% (HPLC), tested by an independent laboratory.

How can I check the purity of NAD+?

The Janoshik Analytical (independent laboratory) certificates we hold are shown on this page for the matching dosage and can be verified directly on the laboratory's website. For a dosage without a published certificate, testing is in progress or available on request.

How should NAD+ be stored?

Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).

How is NAD+ reconstituted in the laboratory?

Sterile bacteriostatic water. The site's dilution calculator helps prepare the desired concentration.

Is NAD+ intended for human use?

No. NAD+ is a research reagent (RUO) intended exclusively for in vitro laboratory research. It is not intended for human or veterinary use, nor for diagnosing, preventing or treating any disease.

References