Melanotan II

Synthetic α-MSH analog — reagent for in vitro study of MC1R / MC4R receptors.

DosagePurity ≥ 99.0% (HPLC)

€64.00per 10 mg vial

i.e. €6.40 per mg

QuantityHalloween 2 + 1

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Janoshik certificateAnalysis no. 75881, purity 99.948% / 99.969%Commissioned by: third-party reportVerify

A question about this product?

Research Use Only — Laboratory use exclusively. Not intended for veterinary, diagnostic or therapeutic use. No indication for in vivo use. To be handled exclusively by qualified personnel.

Literature

What the literature describes

Melanotan II is a non-selective cyclic analog of α-MSH that activates MC1R, MC3R, MC4R, and MC5R. At the hormonal and neurobiological level, studies (PMID 8637402, PMID 15262693) characterized stimulation of melanogenesis via MC1R (pigmentation), as well as activation of hypothalamic MC3R/MC4R pathways involved in the regulation of appetite (documented anorexigenic effect), energy expenditure, and erectile function (via pro-opiomelanocortin neurons modulating nitric oxide at the paraventricular level). MC4R activation alters leptin secretion and satiety signaling. Effects observed in preclinical models include increased eumelanin, reduced food intake, and stimulation of sexual behaviors in rodents. These data come from the scientific literature and are provided strictly for informational purposes in a research context. This product is not intended for veterinary, diagnostic or therapeutic use and is not recommended for any use outside a scientific, professional and research setting. [1][2][3]

Research background: Peptide used as a non-selective reference ligand in the characterization of melanocortin receptors.
Reconstitution (lab): Sterile bacteriostatic water. Dilution calculator

Chemical identity

What the vial contains

Reference data for the compound. Measured values appear on the Janoshik certificate, when published.

Research name: Melanotan II
CAS No.: 121062-08-6
Molecular formula: C50H69N15O9
Molecular weight: 1024.18 g/mol
Specified purity: ≥ 99.0% (HPLC)
Vial content: 10 mg
Storage: Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
Database: PubChem

Independent analysis

Certificate for 10 mg

Report from Janoshik Analytical, an independent laboratory, for this exact dosage. The data below are taken from the report.

Janoshik certificate for this dosageCommissioned by: third-party report

Purity: 99.948% / 99.969%
Janoshik task: #75881
Tested: 22/08/2025

View the report Verify at Janoshik

Questions

Frequently asked questions

What does a vial of Melanotan II contain?

Each vial contains lyophilised Melanotan II, available in 10 mg. Purity ≥ 99.0% (HPLC), tested by an independent laboratory.

How can I check the purity of Melanotan II?

The Janoshik Analytical (independent laboratory) certificates we hold are shown on this page for the matching dosage and can be verified directly on the laboratory's website. For a dosage without a published certificate, testing is in progress or available on request.

How should Melanotan II be stored?

Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).

How is Melanotan II reconstituted in the laboratory?

Sterile bacteriostatic water. The site's dilution calculator helps prepare the desired concentration.

Is Melanotan II intended for human use?

No. Melanotan II is a research reagent (RUO) intended exclusively for in vitro laboratory research. It is not intended for human or veterinary use, nor for diagnosing, preventing or treating any disease.

References