

Cap colour may vary by batch.
For research use only
PT-141
Bremelanotide — selective MC4R/MC3R analog, in vitro study tool for the central melanocortinergic axis.
i.e. €5.90 per mg
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In stock
Shipped within 24 business hours from France, in neutral packaging.
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Research Use Only — Laboratory use exclusively. Not intended for veterinary, diagnostic or therapeutic use. No indication for in vivo use. To be handled exclusively by qualified personnel.
Literature
What the literature describes
PT-141 (Bremelanotide) is a cyclic heptapeptide derived from Melanotan II with increased selectivity for the MC4R and MC3R receptors, and reduced affinity for MC1R (thus minimal pigmentary effect). Preclinical studies (PMID 18552829) characterize a central action at the paraventricular hypothalamic nucleus, modulating central release of nitric oxide and dopamine. At the hormonal level, unlike vasoactive compounds, PT-141 acts centrally without significantly altering systemic blood pressure at pharmacological doses. The studies describe stimulation of copulatory behavior in preclinical models and an effect on satiety via the MC4R-leptin pathway. These data come from the scientific literature and are provided strictly for informational purposes in a research context. This product is not intended for veterinary, diagnostic or therapeutic use and is not recommended for any use outside a scientific, professional and research setting. [1][2][3]
- Research background
- Cyclic heptapeptide used as a pharmacological tool for MC4R signaling on hypothalamic neurons.
- Reconstitution (lab)
- Sterile bacteriostatic water. Dilution calculator
Chemical identity
What the vial contains
Reference data for the compound. Measured values appear on the Janoshik certificate, when published.
- Research name
- PT-141
- CAS No.
- 189691-06-3
- Molecular formula
- C50H68N14O10
- Molecular weight
- 1025.18 g/mol
- Specified purity
- ≥ 99.0% (HPLC)
- Vial content
- 10 mg
- Storage
- Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
- Database
- PubChem
Independent analysis
Certificate for 10 mg
No Janoshik certificate has been published for 10 mg yet. We never show another dosage's report in its place.
Questions
Frequently asked questions
What does a vial of PT-141 contain?
Each vial contains lyophilised PT-141, available in 10 mg. Purity ≥ 99.0% (HPLC), tested by an independent laboratory.
How should PT-141 be stored?
Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
How is PT-141 reconstituted in the laboratory?
Sterile bacteriostatic water. The site's dilution calculator helps prepare the desired concentration.
Is PT-141 intended for human use?
No. PT-141 is a research reagent (RUO) intended exclusively for in vitro laboratory research. It is not intended for human or veterinary use, nor for diagnosing, preventing or treating any disease.
References
Cited sources
- [1]PubMedPMID 31599840PubMed · 31599840View on PubMed
- [2]PMCPMC6819023PMC · PMC6819023View on PMC
- [3]PMCPMC8788464PMC · PMC8788464View on PMC
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