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KissPeptin-10 10 mg vial — Research Use Only

Cap colour may vary by batch.

For research use only

KissPeptin-10

Endogenous KISS1 decapeptide — in vitro research reagent for the study of the hypothalamic-pituitary-gonadal axis.

DosagePurity ≥ 99.0% (HPLC)
€69.00per 10 mg vial

i.e. €6.90 per mg

QuantityHalloween 2 + 1

3 vials: the cheapest item is free at checkout. Estimate for this product alone; the discount is applied at payment, across your whole cart.

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A question about this product?

Research Use Only — Laboratory use exclusively. Not intended for veterinary, diagnostic or therapeutic use. No indication for in vivo use. To be handled exclusively by qualified personnel.

Literature

What the literature describes

KissPeptin-10 is the active decapeptide fragment of the KISS1 protein (human amino acids 112-121: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2). It is the main endogenous agonist of the G protein-coupled receptor GPR54 (KISS1R). Studies (PMID 16309735, 18483150) established that the KISS1/GPR54 pathway is the central physiological switch activating the reproductive axis: it triggers pulsatile GnRH secretion by hypothalamic neurons, downstream stimulating LH and FSH from the pituitary. At the cellular level, KissPeptin-10 activates the phospholipase C / calcium pathway and regulates several ion channels in GnRH neurons. Preclinical work also describes a role in the regulation of puberty and in the coupling between energy status and reproductive function (PMID 29643834). No direct activity on GLP-1, GIP, or GH receptors has been reported. These data come from the scientific literature and are provided strictly for informational purposes in a research context. This product is not intended for veterinary, diagnostic or therapeutic use and is not recommended for any use outside a scientific, professional and research setting. [1][2][3][4]

Research background
Peptide derived from the KISS1 protein used as a reference ligand to characterize the GPR54 (KISS1R) receptor and GnRH secretion in hypothalamic cellular models.
Reconstitution (lab)
Reconstitute with sterile bacteriostatic water. Clear, colorless solution. Dilution calculator

Chemical identity

What the vial contains

Reference data for the compound. Measured values appear on the Janoshik certificate, when published.

Research name
KissPeptin-10
CAS No.
374675-21-5
Molecular formula
C59H84N16O14S
Molecular weight
1217.48 g/mol
Specified purity
≥ 99.0% (HPLC)
Vial content
10 mg
Storage
Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
Database
PubChem

Independent analysis

Certificate for 10 mg

No Janoshik certificate has been published for 10 mg yet. We never show another dosage's report in its place.

No certificate published for this dosage

Questions

Frequently asked questions

What does a vial of KissPeptin-10 contain?

Each vial contains lyophilised KissPeptin-10, available in 10 mg. Purity ≥ 99.0% (HPLC), tested by an independent laboratory.

How should KissPeptin-10 be stored?

Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).

How is KissPeptin-10 reconstituted in the laboratory?

Reconstitute with sterile bacteriostatic water. Clear, colorless solution. The site's dilution calculator helps prepare the desired concentration.

Is KissPeptin-10 intended for human use?

No. KissPeptin-10 is a research reagent (RUO) intended exclusively for in vitro laboratory research. It is not intended for human or veterinary use, nor for diagnosing, preventing or treating any disease.

References

Cited sources

  1. [1]PubMedPMID 16309735PubMed · 16309735View on PubMed
  2. [2]PubMedPMID 23015291PubMed · 23015291View on PubMed
  3. [3]PubMedPMID 18483150PubMed · 18483150View on PubMed
  4. [4]PubMedPMID 29643834PubMed · 29643834View on PubMed

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