Tesamorelin

Stabilized GHRH analog — reference tool for in vitro characterization of the GHRH-R receptor.

DosagePurity ≥ 99.0% (HPLC)

€109.00per 10 mg vial

i.e. €10.90 per mg

QuantityHalloween 2 + 1

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Shipped within 24 business hours from France, in neutral packaging.

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Research Use Only — Laboratory use exclusively. Not intended for veterinary, diagnostic or therapeutic use. No indication for in vivo use. To be handled exclusively by qualified personnel.

Literature

What the literature describes

Tesamorelin is a stabilized analog of human GHRH (1-44) protected against DPP-IV degradation by an N-terminal trans-3-hexenoyl group. Studies (PMID 20554713, PMID 18690162, JAMA fullarticle/1889139) showed that Tesamorelin binds to the GHRH-R receptor of pituitary somatotropic cells, activating the Gαs → cAMP → PKA pathway and stimulating physiological pulsatile release of endogenous GH. Downstream, hepatic IGF-1 increases. At the body level, clinical work (HIV population with lipodystrophy) documented a selective and significant reduction in visceral adipose tissue (−18% over 26 weeks), without loss of subcutaneous tissue or major effect on blood glucose or insulin sensitivity. The studies also describe a favorable modulation of lipid markers (decreased triglycerides). These data come from the scientific literature and are provided strictly for informational purposes in a research context. This product is not intended for veterinary, diagnostic or therapeutic use and is not recommended for any use outside a scientific, professional and research setting. [1][2][3]

Research background: Synthetic peptide used as a pharmacological tool for in vitro study of GHRH-R signaling on pituitary cell lines.
Reconstitution (lab): Sterile bacteriostatic water. Dilution calculator

Chemical identity

What the vial contains

Reference data for the compound. Measured values appear on the Janoshik certificate, when published.

Research name: Tesamorelin
CAS No.: 218949-48-5
Molecular formula: C221H366N72O67S
Molecular weight: 5135.8 g/mol
Specified purity: ≥ 99.0% (HPLC)
Vial content: 10 mg
Storage: Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
Database: PubChem

Independent analysis

Certificate for 10 mg

No Janoshik certificate has been published for 10 mg yet. We never show another dosage's report in its place.

No certificate published for this dosage

All published certificates

Questions

Frequently asked questions

What does a vial of Tesamorelin contain?

Each vial contains lyophilised Tesamorelin, available in 10 mg. Purity ≥ 99.0% (HPLC), tested by an independent laboratory.

How can I check the purity of Tesamorelin?

The Janoshik Analytical (independent laboratory) certificates we hold are shown on this page for the matching dosage and can be verified directly on the laboratory's website. For a dosage without a published certificate, testing is in progress or available on request.

How should Tesamorelin be stored?

Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).

How is Tesamorelin reconstituted in the laboratory?

Sterile bacteriostatic water. The site's dilution calculator helps prepare the desired concentration.

Is Tesamorelin intended for human use?

No. Tesamorelin is a research reagent (RUO) intended exclusively for in vitro laboratory research. It is not intended for human or veterinary use, nor for diagnosing, preventing or treating any disease.

References