

Cap colour may vary by batch.
For research use only
RT-3 (R3)
Triple GLP-1 / GIP / Glucagon agonist — reference reagent for in vitro research on energy metabolism.
i.e. €11.90 per mg
3 vials: the cheapest item is free at checkout. Estimate for this product alone; the discount is applied at payment, across your whole cart.
In stock
Shipped within 24 business hours from France, in neutral packaging.
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Research Use Only — Laboratory use exclusively. Not intended for veterinary, diagnostic or therapeutic use. No indication for in vivo use. To be handled exclusively by qualified personnel.
Literature
What the literature describes
Published literature describes RT-3 (LY3437943) as an agonist of the three receptors GLP-1R, GIP-R and GCG-R, all G protein-coupled receptors. In cell models expressing these human receptors, its activity is measured through cAMP production, which makes it possible to compare its action on each receptor with that of the endogenous ligands (GLP-1, GIP and glucagon). As a reagent, it is used to study the joint signalling of these three receptors in vitro. These data come from the scientific literature and are provided strictly for informational purposes in a research context. This product is not intended for veterinary, diagnostic or therapeutic use and is not recommended for any use outside a scientific, professional and research setting. [1][2][3]
- Research background
- RT-3, referenced as LY3437943 in the literature, is a synthetic peptide studied in vitro for its simultaneous activity on GLP-1, GIP and glucagon receptors. Used exclusively as a research reagent to characterize G protein-coupled receptor signaling in cellular models.
- Reconstitution (lab)
- Reconstitute with sterile bacteriostatic water. Clear, colorless solution. Dilution calculator
Chemical identity
What the vial contains
Reference data for the compound. Measured values appear on the Janoshik certificate, when published.
- Research name
- RT-3 (R3)
- CAS No.
- 2381089-83-2
- Molecular formula
- C221H342N46O68
- Molecular weight
- 4731.3 g/mol
- Specified purity
- ≥ 99.8% (HPLC)
- Vial content
- 10 mg
- Storage
- Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
- Database
- PubChem
Independent analysis
Certificate for 10 mg
Report from Janoshik Analytical, an independent laboratory, for this exact dosage. The data below are taken from the report.
- Purity
- 99.805%
- Batch
- PRT26-10
- Janoshik task
- #205159
- Tested
- 24/07/2026
Questions
Frequently asked questions
What does a vial of RT-3 (R3) contain?
Each vial contains lyophilised RT-3 (R3), available in 5 mg to 40 mg. Purity ≥ 99.8% (HPLC), tested by an independent laboratory.
How can I check the purity of RT-3 (R3)?
The Janoshik Analytical (independent laboratory) certificates we hold are shown on this page for the matching dosage and can be verified directly on the laboratory's website. For a dosage without a published certificate, testing is in progress or available on request.
How should RT-3 (R3) be stored?
Lyophilized: refrigerated (2–8 °C) from receipt, protected from light, or at −20 °C for long-term storage; it tolerates a few days of shipping at room temperature with no expected degradation. Reconstituted: refrigerated (2–8 °C).
How is RT-3 (R3) reconstituted in the laboratory?
Reconstitute with sterile bacteriostatic water. Clear, colorless solution. The site's dilution calculator helps prepare the desired concentration.
Is RT-3 (R3) intended for human use?
No. RT-3 (R3) is a research reagent (RUO) intended exclusively for in vitro laboratory research. It is not intended for human or veterinary use, nor for diagnosing, preventing or treating any disease.
References
Cited sources
- [1]PMCPMC11271400PMC · PMC11271400View on PMC
- [2]PubMedPMID 41216380PubMed · 41216380View on PubMed
- [3]PubMedPMID 41090431PubMed · 41090431View on PubMed
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